Background: KP-1461 is Wellington Socks a prodrug to KP-1212.KP-1212 is a viral mutagen designed to increase viral error rate.Methods: We describe 2 phase I studies: KP1461-101 (double-blind, placebo-controlled, single, escalating doses, 100 to 1600 mg study in 42 non-HIV-infected participants) and KP-1461-102 (double-blind placebo-controlled dose
Rune B Strandby,1 Rikard Ambrus,1 Michael P Achiam,1 Amalie Henriksen,1 Jens P Goetze,2 Niels H Secher,3 Lars B Svendsen11Department of Surgical Gastroenterology; 2Department of Clinical Biochemistry; 3Department of Anesthesiology, Rigshospitalet, University of Copenhagen, Copenhagen, DenmarkPurpose: Changes in plasma pro-atrial natriuretic peptide
An integrated study of Foraminifera, Ostracoda and lithostratigraphy was conducted on samples of the Tepetate Formation from the Arroyo Colorado locality, Baja California Sur (Mexico).Based on the planktonic Foraminifera, Acarinina BLOW DRY SPRAY pentacamerata (latest lower Eocene) and Hantkenina nuttalli (earliest middle Eocene) zones were recogni
Istrian shorthaired hound is an old indigenous Croatian dog breed with historical traces of its origin, which date back to the 14th century.Due to its intelligence and great hunting abilities, it is considered an excellent hunting dog.Despite its ancient origin, there is no data on genetic diversity, population structure, and degree of inbreeding t